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Index > Protein center > ABCC1(Gene name) > Dog
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  • ABCC1 (Gene name),
  • Multidrug resistance-associated protein 1 (Protein name ),  MRP1_CANFA from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    ABCC1(MRP1);
    Protein name:
    Multidrug resistance-associated protein 1;
    Alternative:
    Leukotriene C(4) transporter(LTC4 transporter);ATP-binding cassette sub-family C member 1;
    Organism:
    Dog (Canis familiarisCanis lupus familiaris). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    1531
    Sequence:
    50:
    MALRGFCSAD | GSDPFWEWDV | SWNTSNPDFT | KCFQNTVLVW | VPCCYLWLCF | 
    100:
    PFYFLYLSRH | DRGYIQMTYL | NKTKTALGFV | LWIVCWADLF | YSFWERSWGK | 
    150:
    ILAPVFLVSP | TLLGITMLLA | TFLIQLERRK | GVQSSGIMLT | FWLIALLCAL | 
    200:
    AILRSKIMTA | LKEDAEIDVF | RDVTFYIYFS | LVLIQLVLSC | FSDRPPLFSE | 
    250:
    TIHDLNPCPE | SSASFLSRVT | FWWITGLMVR | GYRQPLESTD | LWSLNKEDTS | 
    300:
    EQVVPVLVKN | WKKECAKSKR | QQRKITYSSK | DPAKPKGGSQ | VDVNEEAEVL | 
    350:
    IVKTPQKERE | PSLFKVLYKT | FGPYFLMSFL | FKALHDLMMF | AGPEILKLLI | 
    400:
    NFVNDKKAPD | WQGYLYTALL | FICACLQTLV | LHQYFHICFV | SGMRIKTAVI | 
    450:
    GAVYRKALVI | TNSARKSSTV | GEIVNLMSVD | AQRFMDLATY | INMIWSAPLQ | 
    500:
    VILALYLLWL | NLGPSVLAGV | AVMILMVPLN | AVMAMKTKTY | QVAHMKSKDN | 
    550:
    RIKLMNEILN | GIKVLKLYAW | ELAFKDKVLA | IRQEELKVLK | KSAYLAAVGT | 
    600:
    FTWVCTPFLV | ALSTFAVYVT | VDKNNILDAQ | KAFVSLALFN | ILRFPLNILP | 
    650:
    MVISSIVQAS | VSLKRLRIFL | SHEELEPDSI | ERRPVKDGGG | ANSITVKNAT | 
    700:
    FTWARSDPPT | LSGITFSIPE | GSLVAVVGQV | GCGKSSLLSA | LLAEMDKVEG | 
    750:
    HVAIKGSVAY | VPQQAWIQND | SLRENILFGR | QLQERYYKAV | IEACALLPDL | 
    800:
    EILPSGDRTE | IGEKGVNLSG | GQKQRVSLAR | AVYCDSDIYL | FDDPLSAVDA | 
    850:
    HVGKHIFENV | IGPKGMLKNK | TRLLVTHSIS | YLPQVDVIIV | MTGGKISEMG | 
    900:
    SYQELLARDG | AFAEFLRTYA | SGDQEQAEQD | DGLTGVSSPG | KEVKQMENGM | 
    950:
    LVTDVAGKQL | QRQLSNSSSY | SGDVSRHHTS | TAELQKAGPK | NEDAWKLVEA | 
    1000:
    DKAQTGQVKL | SVYWDYMKAI | GLFISFLSIF | LFLCNHVASL | VSNYWLSLWT | 
    1050:
    DDPIVNGTQE | HTKIRLSVYG | ALGISQGITV | FGYSMAVSIG | GIFASRRLHV | 
    1100:
    DLLQNVLRSP | MSFFERTPSG | NLVNRFSKEL | DTVDSMIPQV | IKMFMGSLFN | 
    1150:
    VIGACIIILL | ATPIASIIIP | PLGLIYFFVQ | RFYVASSRQL | KRLESVSRSP | 
    1200:
    VYSHFNETLL | GVSVIRAFEE | QERFIRQSDL | KVDENQKAYY | PSIVANRWLA | 
    1250:
    VRLECVGNCI | VLFAALFSVI | SRHSLSAGLV | GLSVSYSLQV | TTYLNWLVRM | 
    1300:
    SSEMETNIVA | VERLKEYSET | EKEAPWQIQE | MAPPSTWPQV | GRVEFRDYGL | 
    1350:
    RYRENLDLVL | KHINITINGG | EKVGIVGRTG | AGKSSLTLGL | FRINESAEGE | 
    1400:
    IIIDDINIAK | IGLHDLRVKI | TIIPQDPVLF | SGSLRMNLDP | FSQYSDEEVW | 
    1450:
    TSLELAHLKD | FVSGLPDKLN | QECAEGGENL | SVGQRQLVCL | ARALLRKTKI | 
    1500:
    LVLDEATAAV | DLETDDLIQS | TIRTQFDDCT | VLTIAHRLNT | IMDYTRVIVL | 
    1531:
    DKGEIRECGQ | PSDLLQQRGL | FYSMAKDAGL | V
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    Pfam:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Dog Multidrug resistance-associated protein 1
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    ELISA Kit for Dog Multidrug resistance-associated protein 1
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    ELISA Kit for Dog Multidrug resistance-associated protein 1
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    E1068c
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    ELISA Kit for Dog Multidrug resistance-associated protein 1
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    ELISA Kit for Dog Multidrug resistance-associated protein 1
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    ELISA Kit for Dog Multidrug resistance-associated protein 1
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    CLIA Kit for Dog Multidrug resistance-associated protein 1
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    U1068d
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    CLIA Kit for Dog Multidrug resistance-associated protein 1
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    U1068m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Dog Multidrug resistance-associated protein 1
    Cat.:
    U1068c
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Dog Multidrug resistance-associated protein 1
    Cat.:
    U1068b
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Dog Multidrug resistance-associated protein 1
    Cat.:
    U1068r
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    Please sign in first.
    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Dog Multidrug resistance-associated protein 1
    Cat.:
    U1068h
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    Polyclonal Antibody for Dog Multidrug resistance-associated protein 1
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    P1068Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Dog Multidrug resistance-associated protein 1
    Polyclonal Antibody for Dog Multidrug resistance-associated protein 1
    Polyclonal Antibody for Dog Multidrug resistance-associated protein 1
    Polyclonal Antibody for Dog Multidrug resistance-associated protein 1
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    P1068Rb-m
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    Polyclonal Antibody for Dog Multidrug resistance-associated protein 1
    Cat.:
    P1068Rb-r
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Dog Multidrug resistance-associated protein 1
    Monoclonal Antibody for Dog Multidrug resistance-associated protein 1
    Monoclonal Antibody for Dog Multidrug resistance-associated protein 1
    Monoclonal Antibody for Dog Multidrug resistance-associated protein 1
    Monoclonal Antibody for Dog Multidrug resistance-associated protein 1
    Monoclonal Antibody for Dog Multidrug resistance-associated protein 1
    Protein for Dog Multidrug resistance-associated protein 1
    Protein for Dog Multidrug resistance-associated protein 1
    Protein for Dog Multidrug resistance-associated protein 1
    Protein for Dog Multidrug resistance-associated protein 1
    Protein for Dog Multidrug resistance-associated protein 1
    Protein for Dog Multidrug resistance-associated protein 1

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    Precision
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    References
    1. 1.
      "Identification and characterization of the canine multidrug resistance-associated protein."
      Ma L. , Pratt S.E. , Cao J. , Dantzig A.H. , Moore R.E. , Slapak C.A.
      Mol. Cancer Ther.1:1335-1342(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;VARIANT SER-149
      strain: Beagle.
      tissue: Heart.
      tissue: Kidney.
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